Sheffield United vs Southampton Prediction, Betting Tips, Lineups & Odds | 30 Sep 2025

Championship Betting Preview: Sheffield United vs Southampton

Sheffield United host Southampton in this Championship clash at Bramall Lane, with kick-off set for 02:45 on Wednesday 1 October. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

Saints to Make Life Tough for Blades

Our stake will be split when taking Southampton +0.25 at odds of 1.68 for this Asian Handicap bet. It means a return in the event of a draw but a bigger payout should the visitors claim a win against Sheffield United.

About to bet on our Asian Handicap pick? Use the latest Stake promo code and read our trusted review of the betting platform before committing to your play.

4 of Last 5 H2H Clashes Have Been Southampton Wins

Sheffield United have now suffered three straight home defeats. In their last game, they won on the road at Kassam Stadium when beating Oxford United 1-0. Chris Wilder's men had 44% possession and totalled two shots on target, with Callum O'Hare netting the winner in the 65th minute.

Southampton played Middlesbrough at home in their previous game. It was a 1-1 draw at St. Mary's. The South Coast team had two shots on goal and boasted 55% possession, while Adam Armstrong found the net.

Head-to-Head Statistics

Southampton haven’t lost any of the past five games against United, with the last encounter seeing them land a penalty shootout EFL Cup win (2-2 AET) at Bramall Lane. The past 5 H2H matches have included four Southampton wins along with a single draw.

Championship		G	W	D	L	GF	GA	GD	GD	P
14	Southampton	8	2	4	2	10	11	-1	10:11	10
24	Sheffield Utd	8	1	0	7	3	15	-12	3:15	3

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United have 3 wins and 7 losses, averaging 0.9 goals from 9.9 attempts and 2.7 shots on goal. Chris Wilder's team have averaged 53.0% possession and 6.5 corners per game, conceding 1.5 goals and 3.8 corners from 12.0 attempts and 4.9 shots on goal.

Callum O'Hare leads the way with 3 goals, Tyrese Campbell has 2, with Kieffer Moore and two others on 1. Harrison Burrows is the leading assists maker on 3, with goalkeeper Michael Cooper keeping 2 clean sheets.

Southampton have won 1, lost 4 and drawn 5, with an average of 0.9 goals from 12.0 attempts and 3.3 shots on goal. There’s been an average of 53.8% possession, 5.4 corners awarded and 5.1 corners against them, while they’ve conceded 1.4 goals from 13.8 attempts and 3.4 shots on goal.

Adam Armstrong and Ryan Manning have scored 2 goals, followed by Cameron Archer with 1. Ryan Fraser and Mateus Fernandes have both had 2 assists, with Aaron Ramsdale notching one clean sheet in the previous 10 games.

Confirmed Lineups

Sheffield United confirmed lineup (4-4-2): Michael Cooper (GK), Japhet Tanganga, Mark McGuinness, Ben Mee, Chiedozie Ogbene, Sydie Peck, Tom Davies, Harrison Burrows, Callum O'Hare, Gustavo Hamer, Tyrese Campbell.

Southampton confirmed lineup (4-2-3-1): Alex McCarthy (GK), Ronnie Edwards, Nathan Wood, Joshua Quarshie, Ryan Manning, Caspar Jander, Shea Charles, Tom Fellows, Finn Azaz, Adam Armstrong, Ross Stewart.

Sheffield United vs Southampton Prediction & Betting Tips

We bring you the complete Sheffield United vs Southampton betting insight, including our top match prediction, correct score forecast, key corners pick, player prop advice and a ready-made bet builder.

Match Prediction

We’re siding with Southampton at 1.68 in this Championship match with a +0.25 goal advantage. It’s expected that they will have an edge and we can therefore feel bullish of a return with this wager.

It’s always a case of checking out the latest Championship team news to make expert football predictions. Then we get to work when it comes to unearthing the stats that are the most valuable.

Key Sheffield United vs Southampton league stats:

• The +0.25 line has been covered by Southampton in 5 of their last 7 games.
• The +0.25 line has been covered by Southampton in 2 of their last 3 games on the road.
• The -0.25 line hasn’t been covered by United in 4 consecutive games at home.
• The -0.25 line hasn’t been covered by United in 7 of their last 10 games.
• The -0.25 line hasn’t been covered by United in 13 of their last 20 games.
• The -0.25 line hasn’t been covered by United in 5 consecutive games against Southampton.

Southampton +0.25 Probability

If you go by the best football betting sites, our pick has a 59.5% chance of delivering a return. However, our experts think that the probability sits between 65-70% taking all factors into consideration. It is therefore regarded as a value wager.

Want to back Southampton to cover the line at bigger odds? Get more juice by taking the Bet Builder route where different legs can be combined to good effect.

Power up your bet with the latest free bets, sign-up bonuses and premium betting offers found in our in-depth guide.

Our Match Prediction

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Correct Score Prediction

Sheffield United 1 - 2 Southampton

We’ve found an attractive bet at odds of 9.00 and it involves Southampton winning 2-1. We like a wager on correct score as there’s the chance to bank a bigger return.

Player Prop Picks

Corners Prediction

Southampton Over 4.5 Corners

Southampton have had over 4.5 corners in nine consecutive games. We think that the value can be found by wagering on Team Corners and you can secure 1.68 that Southampton go over the line.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Sheffield United

Total

10.30 6.50 3.80

Home

10.80 7.20 3.60

Away

9.90 5.90 4.00

Southampton

Total

10.50 5.40 5.10

Home

10.90 4.20 6.70

Away

7.80 4.20 3.60

Latest Corner Odds

Total Corners

Sheffield United Corners

Southampton Corners

Most Corners

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Sheffield United vs Southampton Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Betting Sites Predicting a Close Encounter

Sheffield United are currently available at 2.45 with the bookmakers to defeat Southampton, with the latter priced at odds of 2.80. If you’re siding with the draw in this Championship clash, then it can be backed at 3.40.

There’s the option to get some insurance on your bet by going down the Draw No Bet route. This allows you to back United at 1.76 with a safety net or alternatively opt for Southampton at 1.98.

Under 2.5 Goals is available as the favourite and a bet on this pick means that you don’t want more than two goals to be netted. Punters anticipating that both teams will find the net are able to land 1.74 for the BTTS Yes option.

All of the Championship games see the top betting sites go to town with their service. Bettors can find the best approach from the hundreds of markets which are presented to them each time.

Tyrese Campbell is the First Goalscorer Favourite

There is 3.50 available that Tyrese Campbell finds the net anytime, while the favourite to score the first goal is on offer at 6.00.

Can United Avoid Yet Another Home Defeat?

The past three Sheffield United games at Bramall Lane have ended in defeat. The Blades have finished with four wins, four losses and two draws in the last 10 home matches, scoring an average of 1.20 goals per game and conceding 1.00.

Southampton haven’t won any of their past nine away games. Will Still's side have collected six losses, three draws and one victory in the past 10 away matches, scoring an average of 0.90 goals per game and conceding 2.20.

Southampton were penalty shootout victors (2-2 after 90 mins) against United last time out at Bramall Lane. In addition to a draw, Southampton have been dominant with two wins in the previous 3 H2H games at Bramall Lane.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Sheffield United Home Stats		4-2-4	2.20	1.20	1.00	3	7	4	6
Southampton Away Stats		1-3-6	3.10	0.90	2.20	6	4	7	3

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

Sheffield United vs Southampton Lineups & Team News

Avoid surprises — review the United vs Southampton team news before you bet. We’ll bring you the expected and confirmed lineups for the Championship along with up-to-date injury news.

Sheffield United Team Page Southampton Team Page